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Biblioteca (s) : |
INIA La Estanzuela. |
Fecha : |
08/06/2021 |
Actualizado : |
02/09/2022 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Autor : |
ESTEVEZ M.B.; CASAUX, M.L.; FRAGA, M.; FACCIO, R.; ALBORÉS, S. |
Afiliación : |
MARÍA BELÉN ESTEVEZ, Área de Microbiología, Departamento de Biociencias, Facultad de Química, Universidad de la República, Montevideo, Uruguay./Posgrado en Química, Facultad de Química, Universidad de la República, Montevideo, Uruguay.; MARÍA LAURA CASAUX, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MARTIN FRAGA COTELO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; RICARDO FACCIO, Departamento de Experimentación y Teoría de la Estructura de la Materia y sus Aplicaciones (DETEMA), Facultad de Química, Centro NanoMat and Grupo Física, Universidad de la República, Montevideo, Uruguay.; SILVANA ALBORÉS, Area de Microbiología, Departamento de Biociencias, Facultad de Química, Universidad de la República, Montevideo, Uruguay. |
Título : |
Biogenic silver nanoparticles as a strategy in the fight against multi-resistant salmonella enterica isolated from dairy calves. |
Fecha de publicación : |
2021 |
Fuente / Imprenta : |
Frontiers in Bioengineering and Biotechnology, April 2021, Volume 926, Article number 644014. OPEN ACCESS. Doi: https://doi.org/10.3389/fbioe.2021.644014 |
DOI : |
10.3389/fbioe.2021.644014 |
Idioma : |
Inglés |
Notas : |
Article history:Received: 19 December 2020/Accepted: 31 March 2021/Published: 26 April 2021,
This work was supported by the Comisión Sectorial de Investigación Científica (CSIC), Espacio Interdisciplinario (EI) y Comisión Académica de Posgrado (CAP) (Universidad de la República, Uruguay), Program for the Development of Basic Sciences (PEDECIBA-Química), and Agencia Nacional de Investigación e Innovación (ANII) Uruguay. |
Contenido : |
Abstract: Infectious diseases are one of the most important health problems worldwide, one of the main causes being the development of multi-resistant microorganisms. Likewise,the zoonotic potential of some pathogens and their ability to transfer resistance mechanisms, reduce the therapeutic options in both humans and animals. Salmonella enterica is an important pathogen that affects a wide range of animal species and humans, being Salmonella Typhimurium one of the most frequent serotypes affecting cattle, causing enteritis, diarrhea, and septicemia. The search for alternative therapeutic approaches has gained importance since the emergence of multidrug resistance to antibiotics and periodic outbreaks of salmonellosis. In this sense, the discovery of new drugs and the development of new strategies, such as the use of nanoparticles with antimicrobial activity, are very promising. The aim of this work was the extracellular production of biogenic silver nanoparticles using fungal extracts and the evaluation of their antimicrobial activity against resistant and multi-resistant Salmonella Typhimurium strains. We here demonstrated the potential of the biogenic nanoparticles as effective bacteriostatic and bactericidal agents for use in biomedical applications. In addition, Confocal Raman Microscopy and Atomic Force Microscopy were used to advance the understanding of the antimicrobial mechanism of biogenic nanoparticles against these pathogenic strains, the results of which suggested that the nanoparticles produced damage in several bacterial cell structures. MenosAbstract: Infectious diseases are one of the most important health problems worldwide, one of the main causes being the development of multi-resistant microorganisms. Likewise,the zoonotic potential of some pathogens and their ability to transfer resistance mechanisms, reduce the therapeutic options in both humans and animals. Salmonella enterica is an important pathogen that affects a wide range of animal species and humans, being Salmonella Typhimurium one of the most frequent serotypes affecting cattle, causing enteritis, diarrhea, and septicemia. The search for alternative therapeutic approaches has gained importance since the emergence of multidrug resistance to antibiotics and periodic outbreaks of salmonellosis. In this sense, the discovery of new drugs and the development of new strategies, such as the use of nanoparticles with antimicrobial activity, are very promising. The aim of this work was the extracellular production of biogenic silver nanoparticles using fungal extracts and the evaluation of their antimicrobial activity against resistant and multi-resistant Salmonella Typhimurium strains. We here demonstrated the potential of the biogenic nanoparticles as effective bacteriostatic and bactericidal agents for use in biomedical applications. In addition, Confocal Raman Microscopy and Atomic Force Microscopy were used to advance the understanding of the antimicrobial mechanism of biogenic nanoparticles against these pathogenic strains, the results of which sugges... Presentar Todo |
Palabras claves : |
Antimicrobial; Biogenic nanoparticles; Confocal Raman Microscopy; Multi-resistance; PLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL; Salmonella Typhimurium; TERNEROS LECHEROS. |
Asunto categoría : |
E16 Enfermedades de los animales |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/16669/1/fbioe-09-644014.pdf
https://www.frontiersin.org/articles/10.3389/fbioe.2021.644014/pdf
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Marc : |
LEADER 02991naa a2200277 a 4500 001 1062117 005 2022-09-02 008 2021 bl uuuu u00u1 u #d 024 7 $a10.3389/fbioe.2021.644014$2DOI 100 1 $aESTEVEZ M.B. 245 $aBiogenic silver nanoparticles as a strategy in the fight against multi-resistant salmonella enterica isolated from dairy calves.$h[electronic resource] 260 $c2021 500 $aArticle history:Received: 19 December 2020/Accepted: 31 March 2021/Published: 26 April 2021, This work was supported by the Comisión Sectorial de Investigación Científica (CSIC), Espacio Interdisciplinario (EI) y Comisión Académica de Posgrado (CAP) (Universidad de la República, Uruguay), Program for the Development of Basic Sciences (PEDECIBA-Química), and Agencia Nacional de Investigación e Innovación (ANII) Uruguay. 520 $aAbstract: Infectious diseases are one of the most important health problems worldwide, one of the main causes being the development of multi-resistant microorganisms. Likewise,the zoonotic potential of some pathogens and their ability to transfer resistance mechanisms, reduce the therapeutic options in both humans and animals. Salmonella enterica is an important pathogen that affects a wide range of animal species and humans, being Salmonella Typhimurium one of the most frequent serotypes affecting cattle, causing enteritis, diarrhea, and septicemia. The search for alternative therapeutic approaches has gained importance since the emergence of multidrug resistance to antibiotics and periodic outbreaks of salmonellosis. In this sense, the discovery of new drugs and the development of new strategies, such as the use of nanoparticles with antimicrobial activity, are very promising. The aim of this work was the extracellular production of biogenic silver nanoparticles using fungal extracts and the evaluation of their antimicrobial activity against resistant and multi-resistant Salmonella Typhimurium strains. We here demonstrated the potential of the biogenic nanoparticles as effective bacteriostatic and bactericidal agents for use in biomedical applications. In addition, Confocal Raman Microscopy and Atomic Force Microscopy were used to advance the understanding of the antimicrobial mechanism of biogenic nanoparticles against these pathogenic strains, the results of which suggested that the nanoparticles produced damage in several bacterial cell structures. 653 $aAntimicrobial 653 $aBiogenic nanoparticles 653 $aConfocal Raman Microscopy 653 $aMulti-resistance 653 $aPLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL 653 $aSalmonella Typhimurium 653 $aTERNEROS LECHEROS 700 1 $aCASAUX, M.L. 700 1 $aFRAGA, M. 700 1 $aFACCIO, R. 700 1 $aALBORÉS, S. 773 $tFrontiers in Bioengineering and Biotechnology, April 2021, Volume 926, Article number 644014. OPEN ACCESS. Doi: https://doi.org/10.3389/fbioe.2021.644014
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INIA La Estanzuela (LE) |
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
21/12/2023 |
Actualizado : |
21/12/2023 |
Tipo de producción científica : |
Artículos en Revistas Agropecuarias |
Autor : |
VICENTE, E.; RODRÍGUEZ, G.; GHELFI, B.; LADO, J.; ARRUABARRENA, A.; ARIAS, M.; GONZÁLEZ-ARCOS, M.; ZUNINI, N. |
Afiliación : |
CARLOS ESTEBAN VICENTE CASTRO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; GUSTAVO ROBERTO RODRÍGUEZ LAGOUTTE, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; JOSE BRIAN GHELFI DE SOUZA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; JOANNA LADO LINDNER, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANA ARRUABARRENA PASCOVICH, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MARIANA ARIAS, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MATIAS GONZÁLEZ-ARCOS, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; NICOLAS DANIEL ZUNINI DEL VALLE, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
¿Cómo se obtienen las variedades de boniato?- |
Complemento del título : |
Hortifruticultura. |
Fecha de publicación : |
2023 |
Fuente / Imprenta : |
Revista INIA Uruguay, Diciembre 2023, no.75 p.68-70. |
Serie : |
(Revista INIA; 75). |
ISSN : |
1510-9011 |
Idioma : |
Español |
Contenido : |
Las variedades de boniato más utilizadas en Uruguay fueron generadas por el mejoramiento genético nacional. Las actividades de investigación
se iniciaron en 1973 colectando poblaciones locales e introduciendo variedades extranjeras. |
Palabras claves : |
SISTEMA VEGETAL INTENSIVO - INIA. |
Thesagro : |
BONIATO; IPOMOEA BATATAS; VARIEDADES. |
Asunto categoría : |
F30 Genética vegetal y fitomejoramiento |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/17459/1/Revista-INIA-75-dic-2023-16.pdf
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Marc : |
LEADER 00978naa a2200277 a 4500 001 1064421 005 2023-12-21 008 2023 bl uuuu u00u1 u #d 022 $a1510-9011 100 1 $aVICENTE, E. 245 $a¿Cómo se obtienen las variedades de boniato?-$h[electronic resource] 260 $c2023 490 $a(Revista INIA; 75). 520 $aLas variedades de boniato más utilizadas en Uruguay fueron generadas por el mejoramiento genético nacional. Las actividades de investigación se iniciaron en 1973 colectando poblaciones locales e introduciendo variedades extranjeras. 650 $aBONIATO 650 $aIPOMOEA BATATAS 650 $aVARIEDADES 653 $aSISTEMA VEGETAL INTENSIVO - INIA 700 1 $aRODRÍGUEZ, G. 700 1 $aGHELFI, B. 700 1 $aLADO, J. 700 1 $aARRUABARRENA, A. 700 1 $aARIAS, M. 700 1 $aGONZÁLEZ-ARCOS, M. 700 1 $aZUNINI, N. 773 $tRevista INIA Uruguay, Diciembre 2023, no.75 p.68-70.
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